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Globus Medical (GMED) Q4 FY25 earnings call: guidance and Q&A

Earnings call· Dec 2025 (Q4 FY25)· Health Care· Feb 24, 2026

Source: earnings call transcript

Executive summary

Globus Medical Q4 FY25 — Record Performance Driven by U.S. Spine and Enabling Technologies

Globus Medical delivered a record Q4 FY25, driven by strong U.S. Spine performance and a rebound in Enabling Technologies sales, exceeding synergy targets for NuVasive and achieving early EPS accretion from Nevro. The company is now focused on sustained profitable growth through increased R&D investment, aggressive capital placement strategies, and further integration of its recent acquisitions, while acknowledging potential short-term lumpiness in the Nevro business and continued efforts in international markets.

Highlights

5
  • Full year 2025 revenue reached $2.939 billion, growing 16.7% as reported.

  • Q4 2025 revenue totaled $826.4 million, up 25.7% year-over-year.

  • Non-GAAP EPS for Q4 2025 was $1.28, a 52.1% increase over Q4 2024.

  • Base business U.S. Spine grew 10% in Q4, marking the third consecutive quarter of double-digit growth.

  • Achieved $200 million in NuVasive synergies, exceeding the $170 million target almost a year ahead of schedule.

Concerns

3
  • Nevro business path to growth may not be linear in the short term, with expected choppiness in 2026.

  • International business faced challenges in 2025, particularly in the APAC region, requiring continued focus for growth.

  • Enabling Technologies experienced lumpiness in 2025, with an elongated sales pipeline, though Q4 saw deals close.

Guidance & targets

CategoryTargetConfidence
Full Year 2026 Revenue
$3.18 billion to $3.22 billion
high materiality
High
Full Year 2026 Non-GAAP Fully Diluted EPS
$4.40 to $4.50
high materiality
High
Full Year 2026 Revenue Growth
8.2% to 9.6%
high materiality
High
Full Year 2026 Non-GAAP Fully Diluted EPS Growth
10.6% to 13.1%
high materiality
High
Full Year 2026 Adjusted Gross Profit Margin
69% to 70%
medium materiality
High
Long-term Adjusted Gross Profit Percentage
mid-70s
medium materiality
High
Full Year 2026 R&D Expense
5% to 6% of net sales
medium materiality
High
Full Year 2026 SG&A Expense
38% to 39% of net sales
medium materiality
High
Full Year 2026 Non-GAAP Tax Rate
24% to 25%
low materiality
High
Full Year 2026 CapEx
5% to 6% of net sales
medium materiality
High
Nevro EPS Accretion
Accretive in FY25
high materiality
High

Segment performance

SegmentRevenueYoYQoQMargin
Consolidated
Total revenue for Q4 2025.
Constant Currency Growth: 24.7%
$826.4 million25.7%——
Consolidated
Total revenue for Full Year 2025.
Constant Currency Growth: 16.2%
$2.939 billion16.7%——
Base Business (ex-Nevro)
Full year 2025 base business revenue, excluding Nevro contributions.
$2.6454 billion5%——
Base Business (ex-Nevro)
Q4 2025 base business revenue.
H2 2025 Organic Growth: 8.8%
$726.7 million10.6%——
U.S. Spine
U.S. Spine growth in Q4 2025, continuing momentum from Q3 and Q2.
Q3 Growth: 10%Q2 Day Adjusted Growth: 7.4%Consecutive Growth Weeks: 48
—10%——
Enabling Technologies
Q4 2025 sales, driven by increased EGPS systems.
Record Sales: Dollars and Units
$55.6 million18.5%——
Trauma
Q4 2025 growth, driven by legacy trauma line and precise limb lengthening products.
—27%——
Nevro
Full year 2025 revenue contribution from Nevro. Achieved EPS accretion 15 months ahead of schedule.
FY24 Net Loss: $113 millionFY24 Revenue: $409 millionEPS Accretive: FY25
$293.6 million———
Nevro
Q4 2025 revenue and adjusted EBITDA margin for Nevro.
Q3 Adjusted EBITDA: 16.2%
$99.7 million——21.2%
Musculoskeletal
Q4 2025 consolidated musculoskeletal revenue.
$770.8 million26.3%——
Legacy Globus Musculoskeletal
Q4 2025 legacy Globus musculoskeletal revenue.
$671.1 million9.9%——
U.S.
Q4 2025 consolidated U.S. revenue.
$665.3 million27.5%——
Legacy Globus U.S.
Q4 2025 legacy Globus U.S. revenue, driven by U.S. Spine, neuromonitoring, Trauma, and Enabling Tech.
$576.6 million10.5%——
International
Q4 2025 consolidated international revenue.
Constant Currency Growth: 14.2%
$161.1 million19%——
Legacy Globus International
Q4 2025 legacy Globus international revenue, led by UK, Australia, Germany, Brazil, Mexico, and Poland. Achieved record sales quarter.
Constant Currency Growth: 6.5%
$150.1 million10.9%——

Product announcements

ProductTypeDetails
CREO Tractionlaunch
Reline 3D Towerslaunch
AMS Freehand instrumentslaunch
HEDRON C-MISlaunch
ANTHEM elbow plating systemlaunch

Deals & partnerships

NuVasive Integration of NuVasive business

The merger integration focused on sales retention in 2024 and sales growth in 2025, with significant synergy capture impacting SG&A, COGS, and R&D.

Nevro Acquisition of Nevro for market adjacency in pain management $252.5 million

Acquired in April 2025. Focus in 2025 was on retaining sales and stabilizing the business. Future plans include developing new SCS products, mechanical solutions, cross-selling with legacy Globus products, and competitive recruiting.

Risks & headwinds

Nevro Integration & Growth Linearity Short term (2026)

Path to growth may not be linear in the short term, with expected choppiness in 2026.

Mitigation:Focus on developing new SCS products, mechanical solutions, cross-selling with legacy Globus products, competitive recruiting, and getting back to basics of running the business.

International Business Challenges 2025 (past), ongoing into 2026

Impacted by supply chain shortages early in 2025. More challenges in APAC region (e.g., Japan) and some choppiness in Latam.

Mitigation:Going deeper in existing countries, driving continued growth and sustainability, particularly in APAC and Latam. Expect growth to improve later in 2026.

Enabling Technologies Sales Elongation/Lumpiness 2025 (past), cautiously optimistic for 2026

Pipeline deals experienced elongation during 2025, leading to lumpiness in quarterly sales. Q4 saw deals close.

Mitigation:Getting more flexible in quoting deals, including operating leases, to aggressively drive capital placement and implant pull-through. Not hearing same concerns regarding spending as last year.

Competitive Landscape Ongoing

Competitive landscape continues to evolve, with new robot navigation systems from competitors.

Mitigation:Staying focused on internal objectives, investing in spine portfolio and best-in-class technology, driving successful robotic programs, and leveraging marketability to attract competitive reps. Believe ExcelsiusGPS is well-positioned.

What to watch in Q1 FY26

U.S. Spine Growth Momentum

Q1 FY26
Current 48 consecutive weeks of growth, 10% in Q4 FY25
Target Continued strong growth, sustaining above-market rates

Why it matters

U.S. Spine is the primary driver of overall business performance and profitability.

Our U.S. Spine business grew 10% in Q4 as compared to the prior year quarter, coming off a third quarter where U.S. Spine also grew 10% versus the prior year third quarter. We've seen this trend continue and now sit at 48 weeks of consecutive growth with this momentum continuing thus far into our first quarter of 2026.

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Q&A highlights

Inquired about the sustainability of the 9% H2 2025 base business growth and the path to mid-to-high single digits for 2026, and asked for more detail on the long-term mid-70s adjusted gross margin target.

Keith Pfeil attributed H2 2025 growth to sales force expansion, new product launches (9 in 2024, 6 in 2025), and increased inventory/set production. He noted continued momentum in U.S. Spine into Q1 2026. Kyle Kline reiterated the FY26 adjusted gross profit margin guidance of 69%-70% (at least 100 bps improvement) and explained that gross profit margin cadence typically follows seasonal revenue patterns, with the mid-70s target expected beyond 2026.

“As I look at the year, we did a really nice job growing our sales force with competitive rep conversions. When you think about the products that we've launched, we launched 9 products in spine in 2024 and another 6 in 2025. Those really helped drive some of that growth.”

asked by Shagun Singh Chadha · answered by Keith Pfeil

2 min read 7 chapters

Detailed narrative

Q4 and Full Year 2025 Performance Highlights

Consolidated revenue for Q4 FY25 reached $826.4 million, a 25.7% increase year-over-year, with non-GAAP EPS of $1.28, up 52.1%. Full year 2025 revenue was $2.939 billion, growing 16.7%, and non-GAAP EPS was $3.98, up 30.8%. The base business, excluding Nevro, grew 5% for the full year and 10.6% in Q4, demonstrating accelerated momentum in the second half of the year with 8.8% organic growth.

U.S. Spine Momentum

The U.S. Spine business grew 10% in Q4, following a 10% growth in Q3, and has seen 48 consecutive weeks of growth extending into Q1 2026. This broad-based momentum was driven by successful product launches, including expandable TLIF products, MIS pedicle screws, and power tools like DuraPro, supported by strategic investments in inventory and set production to meet customer demand.

Enabling Technologies Rebound

Q4 Enabling Technology sales were $55.6 million, an 18.5% increase, driven by increased sales of ExcelsiusGPS systems. The company successfully closed pipeline deals that had previously experienced elongation. Management plans to adopt more aggressive pricing and deal flexibility, including operating leases, to drive market share and implant pull-through, positioning the business well for 2026.

Trauma Business Growth

The trauma business delivered approximately 27% growth in Q4, benefiting from a focused strategy on Level 1 and Level 2 trauma centers. Key product launches, such as the ANTHEM elbow plating system in Q3 2025, exceeded expectations in both revenue and demand, contributing to the business's ability to bid on primary vendor contracts.

Nevro Integration and Outlook

Nevro contributed $99.7 million in Q4 revenue with an adjusted EBITDA of 21.2%. The business achieved EPS accretion in FY25, 15 months ahead of initial guidance. While the path to growth may not be linear in the short term, the company plans to focus on developing new SCS products, mechanical solutions, cross-selling with legacy Globus products, and competitive recruiting to drive long-term profitable sales growth.

Synergy Execution Success

Globus Medical achieved $200 million in NuVasive synergies, exceeding the $170 million target almost a year ahead of schedule. Nevro became EPS accretive in FY25, 15 months earlier than the initial Q1 2027 expectation. These synergies primarily impacted SG&A and COGS, contributing to a six-consecutive-quarter expansion in adjusted gross margin and a significant increase in free cash flow generation.

Strategic Focus and Future Investment

The company is moving beyond M&A integration to increase product development investment, sustain above-market sales growth, and achieve operating leverage. It aims to be a procedure-enabling MedTech platform that thoughtfully integrates imaging, navigation, robotics, and implants, focusing on patient selection, surgical techniques, and complementary implants to drive continuous improvement in patient care.

Summary of the company's earnings call; see how call summaries are prepared. Not investment advice.