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MDxHealth (MDXH) Q2 FY26 earnings call: guidance and Q&A

Earnings call· Jun 2026 (Q2 FY26)· Health Care· Aug 13, 2026

Source: earnings call transcript

Executive summary

MDxHealth Q2 FY26 — Strong Sequential Revenue Growth and De-risking

MDxHealth delivered a strong rebound in Q2 FY26, marked by significant sequential revenue acceleration and the successful wind-down of its Resolve UTI business, eliminating a substantial contingent liability. The company is now solely focused on its urology market prostate cancer franchise, leveraging recent study publications and AI initiatives to drive future growth. Management reaffirmed full-year revenue guidance and expects to return to adjusted EBITDA profitability by year-end, supported by a strengthened balance sheet.

Highlights

5
  • Generated a 14% sequential revenue increase, or $3.3 million, representing the largest quarter-over-quarter revenue acceleration in company history.

  • Achieved recovery in tissue-based business with a sequential increase of greater than 1,400 tests, following Q4 and Q1 impacts from sales force restructuring.

  • Successfully transitioned all Resolve customers by the end of Q2, maintaining strong customer credibility.

  • Strengthened balance sheet with a $20 million registered direct financing, resulting in a pro forma cash balance of $39.2 million as of June 30, 2026.

  • Eliminated a $10.4 million contingent liability to Novitas by discontinuing Resolve UTI testing and winding down Plano, Texas lab operations.

Concerns

3
  • Gross margins decreased by 2.9 percentage points to 65.7% compared to 68.6% in Q2 FY25, primarily due to tissue versus liquid mix.

  • Operating loss increased to $5.1 million compared to $1.5 million in Q2 FY25, driven by increased headcount and operating expenses from the ExoDx acquisition.

  • Adjusted EBITDA was negative $2.3 million, down from positive $1.1 million in Q2 FY25, primarily due to ExoDx acquisition-related expenses.

Guidance & targets

CategoryTargetConfidence
Full-year revenue
$110 million to $115 million
high materiality
High
Adjusted EBITDA profitability
positive adjusted EBITDA
high materiality
High

Segment performance

SegmentRevenueYoYQoQMargin
Core Operations (Prostate Cancer Franchise)
Revenue for the second quarter ended June 30, 2026, was $27.2 million, an increase of 16% over the second quarter of 2025. Generated a 14% sequential revenue increase or $3.3 million, representing the largest quarter-over-quarter revenue acceleration in company history. Revenue in the second quarter of 2026 was comprised of 73% from tissue-based tests compared to 96% for the same period last year. Recovery in tissue-based business delivered with a sequential increase of greater than 1,400 tissue-based tests.
Tissue-based tests revenue contribution: 73% of total revenueTissue-based tests sequential increase: >1,400 tests
$27.2 million16%14%—

Deals & partnerships

Existing shareholders Registered direct placement of shares $20 million

On August 11, we executed a $20 million registered direct placement with existing shareholders. After taking this transaction into account, our pro forma cash balance as of June 30, 2026, would have been $39.2 million.

Risks & headwinds

Sales force restructuring and integration impact Q4 FY25 and Q1 FY26

Q4 and Q1 impact on tissue-based business, leading to "choppy" results.

Mitigation:recovery with a sequential increase of greater than 1,400 tissue-based tests in Q2 FY26; sales force focused solely on this significant market opportunity.

Seasonality in Q3 Q3

a little bit of a wildcard

Mitigation:Expects acceleration in Q3 and Q4 in linear-ish overall.

Gross margin compression due to product mix Q2 FY26

decrease of 2.9 percentage points to 65.7% in Q2 FY26 from 68.6% in Q2 FY25.

Mitigation:Expected to be absorbed by revenue growth and return to adjusted EBITDA profitability.

Increased operating expenses from ExoDx acquisition Q2 FY26

Operating loss increased to $5.1 million (vs $1.5 million Q2 FY25); Net loss increased 36% to $9.5 million (vs $7 million Q2 FY25).

Mitigation:confident that our guidance and associated revenue growth will absorb this increase in acquired operating expenses and return to our trend of adjusted EBITDA profitability as we exit this year.

What to watch in Q3 FY26

Full-year revenue guidance achievement

FY26
Current Q2 FY26 revenue $27.2M, 16% YoY growth
Target $110 million to $115 million

Why it matters

Verifies the company's ability to maintain sequential acceleration and meet its annual revenue targets after strategic shifts.

All of this progress in Q2 reinforces our commitment to and confidence in meeting or exceeding our full year guidance of $110 million to $115 million in revenue while returning to adjusted EBITDA profitability as we exit this year.

Find out whether MDXH delivers this. Inve re-checks your case every morning.

Q&A highlights

Inquired if the Q2 sequential increase in tissue-based tests indicated that prior challenges were internal (sales force restructuring) rather than competitive, given competitors' growth.

Management confirmed that the challenges were internal, stemming from sales force restructuring and territory reorganization in Q4 and Q1. They expect Q2 to signal a return to full sales force focus on their core menu, with no disruption to market position.

“I kind of signaled we expected Q4 and Q1 to be a little choppy, really a function of the restructuring of the sales organization, right? We had a territory reorganization and then cross-training of the new reps, remapping of the customer base of the combined businesses, and that's really what we saw.”

asked by Thomas Flaten · answered by Michael McGarrity

1 min read 5 chapters

Detailed narrative

Q2 Performance & Strategic Focus

The company achieved a 14% sequential revenue increase in Q2 FY26, the largest in its history, demonstrating a strong rebound after the discontinuation of Resolve UTI testing. This performance reflects a renewed focus on the core urology market and prostate cancer franchise, which management believes is a "blessing in disguise" for the company's strategic direction.

Resolve UTI Wind-down & De-risking

MDxHealth successfully completed the wind-down of its Resolve UTI business, ceasing operations at its Plano, Texas lab and eliminating a $10.4 million contingent liability to Novitas. This action significantly de-risks the business and allows for a singular focus on the prostate cancer diagnostic pathway.

Sales Force & Integration Recovery

Following a period of sales force restructuring and integration post-ExoDx acquisition in Q4 and Q1, the tissue-based business showed recovery with a sequential increase of over 1,400 tests. The sales team also successfully transitioned hundreds of Resolve customers, primarily prostate cancer customers, to other solutions, demonstrating strong execution and customer relationship management.

Clinical Data & AI Initiatives

The peer-reviewed publication of data from the Oxford ProMPT study is gaining recognition among urology customers. The company also has "clear visibility" into the potential of the landmark Oxford PROTECT study to transform the active surveillance market for prostate cancer, aiming to establish GPS as the only diagnostic test with NCCN Level 1 evidence in this population.

Additionally, AI initiatives are expected to deliver incremental value to customers.

Financial Outlook & Capital Position

The company reaffirmed its full-year revenue guidance of $110 million to $115 million and expects to return to positive adjusted EBITDA by the end of 2026. A recent $20 million registered direct financing strengthened the balance sheet, bringing pro forma cash to $39.2 million as of June 30, 2026, providing significant runway for the business.

Summary of the company's earnings call; see how call summaries are prepared. Not investment advice.