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NeoGenomics (NEO) Q2 FY26 earnings call: guidance and Q&A

Earnings call· Jun 2026 (Q2 FY26)· Health Care· Jul 28, 2026

Source: earnings call transcript

Executive summary

NeoGenomics Q2 FY26 — Strong Clinical Growth and Margin Expansion Drive Raised Guidance

NeoGenomics delivered a strong second quarter, marked by robust clinical revenue growth and significant margin expansion, leading to an upward revision of full-year guidance. While the nonclinical Pharma segment faced headwinds, the company's strategic focus on high-value NGS testing and operational efficiencies continues to drive durable and profitable growth, with new product launches and pipeline advancements positioning it for future expansion.

Highlights

5
  • Total revenue increased 11% year-over-year to $201.7 million, exceeding prior guidance.

  • Clinical revenue grew 14% year-over-year, driven by a 12% increase in AUP and 2% volume growth.

  • NGS revenue grew 26% year-over-year, comprising 1/3 of clinical revenue.

  • Adjusted gross margin expanded 260 basis points year-over-year to 48.1%.

  • Adjusted EBITDA increased 36% year-over-year to $14.4 million.

Concerns

3
  • Nonclinical business revenue declined 15% year-over-year to $14.5 million, with Pharma revenue down 26%.

  • Full-year nonclinical business guidance revised to down high single digits from low to mid-single digits.

  • A $10 million DOJ settlement payment will impact Q3 operating cash.

Guidance & targets

CategoryTargetConfidence
Full-year 2026 Revenue
$802 million to $806 million
high materiality
High
Full-year 2026 Clinical Business Growth
low teens
medium materiality
High
Full-year 2026 NGS Business Growth
mid-20s
high materiality
High
Full-year 2026 RaDaR ST or PanTracer Liquid Revenue
mid-single-digit millions
low materiality
High
Full-year 2026 Nonclinical Business Growth
down high single digits
medium materiality
High
Q3 2026 Revenue Growth
approximately 10%
medium materiality
High
Q4 2026 Revenue Growth
above 10%
medium materiality
High
Full-year 2026 Gross Margin Improvement
approximately 100 to 150 basis points
high materiality
High
Full-year 2026 Adjusted EBITDA
$56 million to $58 million
high materiality
High
Q3 and Q4 2026 Adjusted EBITDA Growth
low 30s year-over-year
medium materiality
High
Nonclinical segment year-over-year growth
return to growth
medium materiality
Medium
Next-generation whole genome sequencing MRD assay data generation
generate data
medium materiality
High
Next-generation whole genome sequencing MRD assay clinical launch
potential clinical launch
high materiality
Medium
RaDaR ST additional indications approval
before the end of the year
high materiality
High
RaDaR ST third indication approval
somewhere in the first half -- latter part of the first half of 2027
high materiality
Medium
Commercial representatives count
exceed 160
low materiality
High
G&A as percent of revenue
lower than 30%
medium materiality
Medium

Segment performance

SegmentRevenueYoYQoQMargin
Clinical Business
Driven by strong AUP growth and volume increase, with NGS being a significant contributor and mix shift towards higher-value testing.
AUP growth: 12%Test volumes growth: 2%NGS revenue growth: 26%NGS revenue as % of clinical revenue: 33%5 NGS products (since 2023) growth: 30%5 NGS products (since 2023) as % of total clinical revenue: 26%Large NGS panels growth: >20%
—14%——
Nonclinical Business
Weakness in Pharma business partially offset by ODS growth, leading to a decline in the overall nonclinical segment.
Pharma revenue decline: 26%Oncology Data Solutions (ODS) growth: 17%Pharma revenue as % of total revenue: 5%
$14.5 million-15%——

Product announcements

ProductTypeDetails
PTENlaunch

Deals & partnerships

Epic Aura Workflow integration

Initial integrations announced in April, expected benefits to begin in 2027.

Risks & headwinds

Pharma business decline Q2 FY26 and full-year FY26

down 26% in Q2 FY26; full-year guidance revised to down high single digits

Mitigation:Taking corrective actions, committed to returning to year-over-year growth in 2027, Q2 bookings at all-time highs.

Higher freight costs and fuel surcharges Q2 FY26

impacted gross margin

Mitigation:Offset by AUP growth, volume leverage, and Lab of the Future efficiencies.

DOJ settlement cash impact Q3 FY26

$10 million payment

Mitigation:Already reserved for in financials.

Policy and regulatory changes (PAMA, CRASH, ACA) 2027

not anticipated to be significant impact

Mitigation:Assessing initiatives, working with ACLA, portfolio assessment.

What to watch in Q3 FY26

RaDaR ST MolDX Indications Approval

by year-end 2026
Current 2 indications approved; 2 submitted prior to Q2; 1 submitted in Q2
Target Approval of 2 additional indications

Why it matters

These approvals are key to expanding the addressable market for RaDaR ST and driving future revenue acceleration, particularly in 2027 and beyond.

And we still believe that the 2 that we spoke about previously, we should receive reimbursement before the -- at the end of the year.

Find out whether NEO delivers this. Inve re-checks your case every morning.

Q&A highlights

Given strong Q1/Q2 NGS growth (26%), how should investors think about H2, considering new product launches and potential tough comps? Is the mid-20s guidance conservative?

Management believes NGS growth is durable, driven by intentional shift to large panels and strong performance of 5 key products. The mid-20s guidance reflects strong H1 performance. NGS volume growth was 14% and AUP growth was 12% in Q2.

“So Dave, our view of this is we think we have a very durable position with NGS now. As you said, we exited '25 at about 22% growth, and that's why we guided below 20s. Now in the first quarter of '26 -- we did 26% in Q1, and we matched that again in Q2 at 26%. That's why we're raising the guide to the mid-20s now.”

asked by David Westenberg · answered by Anthony Zook

2 min read 6 chapters

Detailed narrative

Strong Clinical Performance and NGS Momentum

NeoGenomics' clinical business demonstrated robust growth of 14% year-over-year, significantly exceeding expectations. This performance was primarily fueled by a 12% increase in average unit price (AUP) and a 2% rise in test volumes. Next-generation sequencing (NGS) revenue was a key driver, growing 26% year-over-year and now constituting one-third of total clinical revenue, reflecting a successful strategic shift towards higher-value testing.

Nonclinical Business Headwinds and Strategic Reassessment

The nonclinical segment, particularly the Pharma business, faced continued headwinds, resulting in a 15% year-over-year decline in revenue. While Pharma bookings showed significant improvement in Q2, the pull-through rate from prior bookings was lower than anticipated, leading to a revised full-year guidance for the nonclinical segment.

Management views the Pharma business as opportunistic, providing early market access and R&D leverage, but emphasizes that the clinical business remains the core strategic focus.

Significant Margin Expansion and Operational Efficiencies

The company achieved substantial margin improvement, with adjusted gross margin expanding by 260 basis points year-over-year to 48.1%. This was driven by strong AUP growth, volume leverage, and efficiencies gained from the "Lab of the Future" initiative. This program encompasses digital pathology, AI-assisted lab automation, instrument upgrades, and footprint optimization, including the successful transition of PanTracer LBx to the NovaSeq X platform for improved throughput and cost efficiency.

Product Launches and Pipeline Advancements

NeoGenomics is actively converting recent product launches, such as the PanTracer Family and RaDaR ST, into commercial traction. These products target a combined $33 billion market opportunity in therapy selection and MRD. Early feedback is encouraging, with RaDaR ST orders showing strong attachment rates to other NeoGenomics tests.

The pipeline continues to advance, including a next-generation whole genome sequencing MRD assay on track for 2027 data generation and a potential 2029 clinical launch, and the recent FDA-approved PTEN companion diagnostic for prostate cancer.

Commercial Reorganization and Customer Experience

The commercial team has been reorganized into two dedicated ecosystems, one for oncology and one for pathology, to enhance focus and accountability. This strategic shift aims to optimize sales motions for different market dynamics, leveraging the company's strong leadership in hematology to expand its broader portfolio.

The company maintains an industry-leading Net Promoter Score in the high 70s, reflecting its commitment to customer experience and workflow integration, as demonstrated by a recent lung cancer patient workflow optimization.

Strengthened Capital Structure and Financial Discipline

NeoGenomics successfully raised $316 million through a convertible senior notes offering, extending debt maturity from 2028 to 2032 and repurchasing $25 million of common stock to reduce potential dilution. The company generated $20 million in operating cash and ended the quarter with $145.5 million in cash and cash equivalents.

Operating expense discipline, particularly an $8 million decline in G&A, contributed to a 36% increase in adjusted EBITDA, supporting continued investment in sales and R&D.

Summary of the company's earnings call; see how call summaries are prepared. Not investment advice.