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Bio-Techne (TECH) Q3 FY26 earnings call: guidance and Q&A

Earnings call· Mar 2026 (Q3 FY26)· Health Care· May 6, 2026

Source: earnings call transcript

Executive summary

Bio-Techne Q3 FY26 — Mixed Market, Strong Pharma, Spatial Biology Growth

Bio-Techne navigated a mixed market in Q3 FY26, with strong performance from large pharma and stabilizing U.S. academic demand, but continued softness in emerging biotech. The company experienced a 400 basis point headwind from specific cell therapy and OEM order timing, resulting in a 2% organic revenue decline. Strategic brand alignment and leveraging AI are key initiatives, with a positive outlook for fiscal 2027 as market conditions are expected to normalize and company-specific headwinds abate.

Highlights

5
  • Spatial Biology portfolio delivered mid-teens growth, with COMET platform growing over 65% and achieving a record backlog.

  • GMP protein portfolio grew nearly 50% year-over-year when excluding two fast track cell therapy customers.

  • Large pharma customers delivered low double-digit growth for the sixth consecutive quarter.

  • China end market achieved positive organic growth for the fourth consecutive quarter (low single digits).

  • Adjusted operating margin improved sequentially to 34.2%, representing a 310 basis point improvement over fiscal Q2.

Concerns

5
  • Overall organic revenue declined 2% for the quarter.

  • Emerging biotech revenues declined high single digits, offsetting large pharma strength.

  • Protein Sciences organic revenue declined 4% (or 2% underlying excluding timing impacts).

  • Bio-Techne Diagnostics declined low single digits due to order timing from certain large customers.

  • Q4 FY26 organic growth is expected to be approximately flat.

Guidance & targets

CategoryTargetConfidence
Q4 FY26 Organic Growth
approximately flat
high materiality
High
Q4 FY26 Underlying Organic Growth (excluding cell therapy headwinds)
low single-digit
medium materiality
High
Q4 FY26 Margin Expansion
approximately 100 basis points
medium materiality
High
FY27 Organic Growth
at least mid-single-digit growth
high materiality
High

Segment performance

SegmentRevenueYoYQoQMargin
Protein Sciences
Operating margin down 140 bps year-over-year due to unfavorable product mix and volume deleverage, partially offset by profitability initiatives. Growth was led by proteomic analysis instruments, benefiting from large pharma and academic strength. Core reagents impacted by challenging biotech environment and U.S. government shutdown effects.
Organic revenue decline: 4%Foreign exchange benefit: 3%Organic growth (excluding cell therapy and OEM timing): +2%Proteomic analysis instrument franchise growth: double-digit (academic), mid-single-digit (overall)Core portfolio of research reagents and assays decline: mid-single digitsCore portfolio decline (excluding commercial supply timing): low single digits
$226.2 million-1%—44.2%
Diagnostics and Spatial Biology
Segment operating margin improved from 9.4% last year, driven by the Exosome Diagnostics divestiture and productivity initiatives, partially offset by unfavorable mix among OEM customers. Expect continued margin expansion with COMET Spatial Biology platform scaling.
Exosome Diagnostics divestiture impact: -8%Foreign exchange benefit: 1%Organic growth: 3%Bio-Techne Diagnostics decline: low single digitsSpatial Biology growth: mid-teensCOMET platform growth: over 65%RNA scope portfolio growth: high single digitsBio-Techne Diagnostics growth (trailing 12-month): low single digits
$85.6 million-4%—12.1%

Product announcements

ProductTypeDetails
Ella benchtop immunoassay platformexpansion

Deals & partnerships

Wilson Wolf Bio-Techne currently owns 20% of Wilson Wolf and plans to acquire the remainder.

Wilson Wolf manufactures the market-leading product line of single-use bioreactors called the G-Rex. It delivered low double-digit growth on a trailing 12-month basis with EBITDA margins north of 70%.

Risks & headwinds

Emerging Biotech Spending Lag Near-term (Q4 FY26)

Revenues declined high single digits in Q3 FY26, despite funding rebounds of >90% in calendar Q2 2025 and 50% in calendar Q3 2025.

Mitigation:Increased engagement and higher opportunity funnel reported by commercial teams; historical lag of 2-3 quarters between funding and spending suggests recovery in H1 FY27.

Cell Therapy Customer Timing Impact Q3 FY26, Q4 FY26

3% headwind to Q3 FY26 revenue; expected 150 basis point headwind to Q4 FY26 growth.

Mitigation:Headwind moderates in Q4 FY26 and will be fully out of comparisons as of FY27, as customers advance through Phase III trials and accelerate potential commercial timelines.

OEM Commercial Supply Order Timing Q3 FY26

1% headwind to Q3 FY26 revenue.

Mitigation:Order was received in Q2 FY26 instead of Q3 FY26, impacting Q3 comparisons but not a recurring issue.

Unfavorable Product Mix and Volume Deleveraging Q3 FY26

Adjusted gross margin down 120 bps year-over-year; adjusted operating margin down 70 bps year-over-year.

Mitigation:Ongoing profitability initiatives and structural streamlining; expected margin expansion in Q4 FY26 commensurate with scaling of COMET Spatial Biology platform.

U.S. Academic Market Frailty Near-term

Returned to low single-digit growth, but described as 'frail market'.

Mitigation:Stabilization and gradual improvement expected; increased NIH outlays and budget increases reduce funding uncertainty.

What to watch in Q4 FY26

Emerging Biotech Spending Inflection

H1 FY27
Current declined high single digits
Target meaningful uptick in growth

Why it matters

This is the biggest swing factor for growth acceleration, with a typical 2-3 quarter lag between funding and spending.

While we can start to see improvement in the biotech end market as early as our June quarter, our base case is that we won't see a meaningful uptick in growth until the first half of our fiscal year 2027.

Find out whether TECH delivers this. Inve re-checks your case every morning.

Q&A highlights

Given the step-down in emerging biotech revenue to high single-digit decline, what were the intra-quarter trends, and what is the outlook for improvement?

Management was surprised by the high single-digit decline in emerging biotech, as funding had rebounded significantly. They noted that while late-stage biotech funding was up, early-stage funding (which impacts core reagents) was down. Sales force interactions are increasing, but they are maintaining a cautious forecast for Q4, assuming no clear improvement yet, but expect a recovery in H1 FY27.

“But you're right. It did step down to negative high single digits instead. And that really is the whole for our quarter, and it fits very nicely to exactly the gap in our biotech end market.”

asked by Matthew Larew · answered by Kim Kelderman

3 min read 7 chapters

Detailed narrative

Market Dynamics and Funding Trends

Bio-Techne observed a divergence in its end markets during Q3 FY26. Large pharmaceutical customers continued their strong performance with low double-digit growth for the sixth consecutive quarter, driven by sustained investment. In contrast, emerging biotech revenues declined high single digits, reflecting a lag in spending despite a significant rebound in biotech funding activity in calendar Q2 and Q3 2025.

The U.S. academic market showed signs of stabilization, returning to low single-digit growth, supported by improved NIH outlays and budget increases. China continued its momentum with low single-digit growth for the fourth consecutive quarter, driven by increasing demand in advanced therapeutics.

Impact of Cell Therapy and OEM Order Timing

The company's Q3 organic revenue decline of 2% was significantly impacted by specific timing issues. Order timing related to two cell therapy customers with FDA Fast Track designation and a large OEM commercial supply order created a combined 400 basis point headwind.

Excluding these factors, the underlying organic revenue growth for the quarter was 2%. Management expects the cell therapy headwind to moderate to approximately 150 basis points in Q4 FY26 and to be fully out of comparisons by FY27, positioning the company for accelerated growth.

Strategic Brand Alignment

In April, Bio-Techne announced a strategic brand alignment, streamlining its portfolio from ten brands to three: R&D Systems, Bio-Techne Spatial Biology, and Bio-Techne Diagnostics. This initiative aims to simplify customer engagement across the research to clinical continuum and better align products with customer workflows from discovery through translational research and diagnostic applications.

The new structure is also intended to enhance visibility of solutions on digital and AI-driven platforms.

AI's Influence on Operations and Drug Discovery

Artificial intelligence is increasingly impacting Bio-Techne's internal operations and customer drug discovery processes. Internally, AI is leveraged to design novel proteins with enhanced properties, trained on five decades of proprietary data. From a customer perspective, AI accelerates early-stage drug discovery, particularly target discovery, which is expected to expand viable programs.

This drives demand for high-quality biological data, benefiting Bio-Techne's spatial biology and proteomic analysis platforms, and fuels demand for specific reagents and assays for biological validation.

Segment Performance Highlights

The Protein Sciences segment saw a 4% organic revenue decline, but an underlying growth of 2% excluding timing impacts. GMP protein revenue grew nearly 50% (excluding specific customers), and proteomic analysis instruments delivered mid-single-digit growth. The core reagent and assay portfolio declined mid-single digits.

The Diagnostics and Spatial Biology segment achieved 3% organic growth, with the COMET multiomic Spatial Platform growing over 65% and RNA scope portfolio increasing high single digits. Bio-Techne Diagnostics declined low single digits due to order timing.

Financial Performance and Capital Allocation

Adjusted EPS for Q3 FY26 was $0.53, down $0.03 year-over-year, with a $0.02 favorable FX impact. GAAP EPS was $0.32, up from $0.14. Adjusted gross margin was 70.4%, down from 71.6% but up 190 basis points sequentially, impacted by unfavorable product mix.

Adjusted operating margin was 34.2%, down 70 basis points year-over-year, reflecting mix and volume deleverage partially offset by productivity initiatives. The company generated $86.7 million in operating cash flow and returned $12.5 million to shareholders via dividends, maintaining a strong balance sheet with $209.8 million in cash and leverage well below 1x EBITDA.

M&A remains a top capital allocation priority.

Outlook and Fiscal 2027 Expectations

For Q4 FY26, Bio-Techne expects approximately flat organic growth, with underlying low single-digit growth excluding cell therapy headwinds. This outlook assumes Q3 market conditions persist. Management is optimistic for fiscal 2027, anticipating an acceleration in growth as biotech funding translates into customer spending, academic conditions normalize, company-specific timing headwinds roll off, and the company laps easier year-over-year comparisons.

They expect to achieve at least mid-single-digit growth in FY27.

Summary of the company's earnings call; see how call summaries are prepared. Not investment advice.