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    VTRS
    Earnings call· Dec 2025(Q4 FY25)

    Viatris Q4 FY25 earnings call VTRS

    Feb 26, 2026 Source

    Executive summary

    Viatris Q4 FY25 — Strategic Review Positions for Sustained Growth

    Viatris concluded a strong FY25, delivering solid financial results and advancing its pipeline, positioning the company for a period of sustained growth starting in 2026. A comprehensive strategic review identified $650 million in gross cost savings, enabling reinvestment into growth drivers and commercial execution, while the company navigates regional pricing pressures and product losses of exclusivity. The company expects 2026 to be a stabilization year, with structural expansion becoming more visible as savings are realized and new products launch.

    Highlights

    5
    • Total revenues of $14.3 billion in FY25, representing approximately 2% growth versus '24 (excluding Indore Impact).

    • Adjusted EBITDA of $4.2 billion in FY25, reflecting solid operating performance.

    • Over $1 billion in capital returned to shareholders through dividends and share repurchases in FY25.

    • Achieved 5 positive Phase III readouts and significant regulatory progress on multiple assets in FY25.

    • Identified approximately $650 million in gross cost savings over a 3-year period from enterprise-wide strategic review.

    Concerns

    5
    • Anticipated mid-year Amitiza LOE in Japan impacting the JANZ segment in 2026.

    • Regulatory pricing challenges in Japan and Australia impacting the JANZ segment in 2026.

    • Nashik, India facility fire temporarily suspended manufacturing, with operations expected to resume in April.

    • Adjusted gross margins expected to be modestly lower year-over-year in 2026 due to anticipated losses of exclusivity and mix shift.

    • Approximately $40 million in TSA income related to divestitures in 2025 will not recur in 2026.

    Guidance & targets

    27
    CategoryTargetConfidence
    Total Revenues Growth
    approximately 2%
    high materiality
    High
    Adjusted EBITDA Growth
    approximately 2%
    high materiality
    High
    Gross Cost Savings
    $650 million
    high materiality
    High
    Reinvestment from Cost Savings
    up to $250 million
    medium materiality
    High
    Net Cost Savings
    $400 million
    high materiality
    High
    Cost Savings Phasing (2026)
    roughly 30%
    medium materiality
    High
    Cost Savings Phasing (2027)
    additional 30%
    medium materiality
    High
    Cost Savings Phasing (2028)
    remaining approximately 40%
    medium materiality
    High
    New Product Revenues
    $450 million to $550 million
    medium materiality
    High
    Developed Markets Net Sales Growth
    2%
    medium materiality
    High
    Europe Growth
    4%
    medium materiality
    High
    North America Growth
    flat
    medium materiality
    High
    Emerging Markets Growth
    6%
    medium materiality
    High
    Greater China Growth
    3%
    medium materiality
    High
    Gross Leverage Target
    2.8x to 3.2x
    medium materiality
    High
    Regulatory Decisions
    6 product candidates
    high materiality
    High
    New Product Approvals (Generics)
    more than 100
    low materiality
    High
    Effexor GAD Japan Regulatory Decision
    March this year
    high materiality
    High
    Pitolisant Japan Regulatory Decisions
    second half of 2026
    medium materiality
    High
    Phentolamine Ophthalmic Solution PDUFA Goal Date
    October 17, 2026
    medium materiality
    High
    Low-dose Estrogen Weekly Patch PDUFA Goal Date
    July 30, 2026
    medium materiality
    High
    Fast-acting Meloxicam NDA Submission
    by the end of this month
    medium materiality
    High
    Sotagliflozin Regulatory Decision
    later this year
    medium materiality
    High
    Selatogrel Phase III Full Enrollment
    by the end of this year
    medium materiality
    High
    Norelgestromin Only Weekly Patch Phase III Enrollment Completion
    first half of this year
    low materiality
    High
    Nefecon Japan Top Line Readout
    first half of this year
    medium materiality
    High
    Indore Recovery (Top Line)
    a little less than 1%
    low materiality
    High

    Segment performance

    4
    SegmentRevenueYoYQoQMargin
    Greater China
    Expected year-over-year growth driven primarily by cardiovascular products sensitive to proactive patient choice. Confidence stems from maximizing well-established commercial presence across retail, private hospitals, and e-commerce channels, seeing continued growth for retail-oriented products.
    3%
    Europe
    Expected year-over-year growth benefiting from several tailwinds: increased contributions from new product revenue (led by apixaban and paliperidone), continued growth in key markets (France and Italy), some supply recovery from Indore, and strong performance in key brands like Creon and Brufen.
    4%
    North America
    Expected to be flat year-over-year as new product revenues (primarily from complex products) and ongoing strength from existing products (Breyna, Estradiol TDS, Xulane) are expected to offset certain competitive impacts, including the Isosulfan Blue LOE.
    flat
    Emerging Markets
    Expected year-over-year growth primarily driven by expansion in key growth markets (Turkey, Mexico, India, Brazil), new product revenue contributions, and some supply recovery in the ARV business. These benefits are expected to more than offset pricing headwinds in certain Asian markets.
    6%

    Operational metrics

    27
    Total Revenues
    $3.7 billionup 1% versus prior year (excluding Indore Impact)
    Q4 2025

    Total revenues for the fourth quarter of 2025.

    Total Revenues
    $14.3 billionup 2% versus prior year (excluding Indore Impact)
    FY 2025

    Total revenues for full-year 2025, in line with expectations.

    Adjusted EBITDA
    $4.2 billion
    FY 2025

    Adjusted EBITDA for full-year 2025, reflecting solid operating performance.

    Adjusted EPS
    $2.35
    FY 2025

    Adjusted EPS for full-year 2025.

    Capital Returned to Shareholders
    over $1 billion
    FY 2025

    Total capital returned to shareholders in 2025.

    Gross Cost Savings (Strategic Review)
    $650 million
    3-year period

    Gross cost savings identified from the enterprise-wide strategic review, with full run rate benefits realized in 2029.

    Reinvestment from Cost Savings
    up to $250 million
    3-year period

    Amount planned for reinvestment from cost savings to enhance growth and competitiveness.

    Net Cost Savings (Strategic Review)
    $400 million
    3-year period

    Net cost savings after reinvestment from the strategic review.

    Cost Savings Phasing
    roughly 30%
    FY26

    Expected portion of total cost savings to be realized in 2026.

    Cost Savings Phasing
    additional 30%
    FY27

    Expected portion of total cost savings to be realized in 2027.

    Cost Savings Phasing
    remaining approximately 40%
    FY28

    Expected portion of total cost savings to be realized in 2028.

    Cost Savings Split
    evenly balanced
    3-year period

    Distribution of gross cost savings between SG&A and COGS.

    Cost Savings Source (Headcount)
    about 50%
    3-year period

    Portion of gross cost savings coming from headcount reductions.

    New Product Revenues
    $450 million to $550 million
    FY26

    Anticipated new product revenues for full-year 2026.

    Developed Markets Net Sales Growth
    2%year-over-year
    FY26

    Expected year-over-year growth for developed markets in 2026.

    Europe Growth
    4%year-over-year
    FY26

    Expected year-over-year growth for Europe in 2026.

    North America Growth
    flatyear-over-year
    FY26

    Expected year-over-year growth for North America in 2026.

    Emerging Markets Growth
    6%year-over-year
    FY26

    Expected year-over-year growth for Emerging Markets in 2026.

    Greater China Growth
    3%year-over-year
    FY26

    Expected year-over-year growth for Greater China in 2026.

    Adjusted Gross Margin
    modestly loweryear-over-year
    FY26

    Expected trend for adjusted gross margins in 2026, primarily due to LOEs and mix shift.

    Adjusted SG&A
    declineyear-over-year
    FY26

    Expected trend for adjusted SG&A as a percentage of sales, reflecting net benefits from strategic review.

    Adjusted R&D
    flatversus prior year
    FY26

    Expected trend for adjusted R&D spend in 2026.

    TSA Income
    $40 million
    FY25

    TSA income related to divestitures in 2025, which will not recur in 2026.

    Cash Available for Deployment
    over $2.5 billion
    FY26

    Expected cash available for deployment in 2026.

    Restructuring Costs (Strategic Review)
    about $250 million
    FY26

    Estimated one-time costs in 2026 necessary to achieve the strategic review savings.

    Biocon Monetization Taxes
    $110 million
    FY26

    Taxes associated with the Biocon monetization, reported as operational outflows.

    Divestiture-related Cash and Costs/Taxes
    about $320 million
    FY26

    Divestiture-related cash and costs/taxes included in the total cash outflow for 2026.

    Industry KPIs

    6
    MetricValueDetails
    EPS revenue guidanceapproximately 2% total revenue and adjusted EBITDA growth%
    Pricing policy impactmandatory price decreases
    Pipeline clinical milestones5 positive Phase III readouts
    Regulatory approvals filings6 product candidates
    Geographic regional revenue growthDeveloped Markets 2%, Europe 4%, North America flat, Emerging Markets 6%, Greater China 3%%
    Business development capacity deal appetiteover $2.5 billionUSD

    Deals & partnerships

    2
    Aculys PharmaAcquisition of Aculys Pharma in Japan

    Part of 60 regional transactions completed in 2025 to support the base business.

    Multiple60 regional business development transactions

    Targeted accretive regional business development, including the acquisition of Aculys Pharma.

    Risks & headwinds

    8
    Indore Facility Impact2025

    $325 million headwind

    Mitigation: Built operational redundancies, alternative supply sources, plant requalified, ready for reinspection in 2026. Lenalidomide portion not expected to recur in 2026.

    Nashik, India Facility Fireoperations expected to resume beginning in April

    temporary suspension of manufacturing

    Mitigation: Potential impact considered in 2026 financial guidance.

    Regulatory Pricing Challenges2026

    impacting JANZ segment

    Mitigation: Launching strategic products like Effexor and pitolisant to support future performance for the region.

    Amitiza Loss of Exclusivity (LOE)mid-year 2026 (Japan)

    anticipated impact

    Mitigation: Expected to launch important strategic products in 2026, including Effexor and pitolisant, to support future performance for the region.

    Adjusted Gross Margin Decline2026

    modestly lower year-over-year

    Mitigation: Expected to benefit from the realization of cost savings and the scaling of higher-margin products over time.

    TSA Income Non-recurrence2026

    $40 million not recurring

    Pricing Headwinds2026 (certain Asian markets)

    offsetting growth

    Mitigation: Primarily driven by expansion in key growth markets and new product revenue contributions in Emerging Markets.

    Competitive Impacts2026 (North America)

    offsetting new product revenues

    Mitigation: New product revenues (complex products) and ongoing strength from existing products (Breyna, Estradiol TDS, Xulane) are expected to offset these impacts.

    What to watch in Q1 FY26

    5

    Effexor GAD Japan Regulatory Decision

    March 2026
    CurrentUnder review
    TargetApproval

    Why it matters

    Potential first and only treatment for generalized anxiety disorder in Japan, representing an important medical milestone.

    In Japan, we expect a regulatory decision for Effexor for the treatment of generalized anxiety disorder in March this year.

    Q&A highlights

    8

    Asked about the path to mid-single-digit revenue growth, confidence in 6 potential approvals, and the timing of the $400 million net savings from the strategic review.

    Scott Smith outlined the growth path through base business growth, upcoming launches (Effexor, pitolisant, Spydia, low-dose estrogen patch, Ryzumvi, meloxicam), future data readouts (selatogrel, cenerimod), and capital deployment for accretive assets. Doretta Mistras detailed the savings phasing: 30% in '26, 30% in '27, 40% in '28.

    We anticipate roughly 30% in '26, an additional 30% in '27 and then the remaining approximately 40% in 2028.

    asked by Glen Santangelo · answered by Scott Smith, Theodora Mistras

    2 min read6 chapters

    Detailed Narrative

    01

    Strategic Review and Cost Optimization

    Viatris completed an enterprise-wide strategic review, identifying $650 million in gross cost savings over three years, with $250 million planned for reinvestment. These savings are expected to be evenly split between SG&A and COGS, phased over 2026-2028, aiming to strengthen competitiveness and support sustainable growth. The review focused on modernizing the organization post-divestitures and optimizing infrastructure, with approximately 50% of savings from headcount reductions and the remainder from COGS efficiencies, inventory management, and support structures.

    02

    Pipeline and Regulatory Milestones

    The company anticipates 8 regulatory approvals for 6 product candidates in 2026, including Effexor and pitolisant in Japan, phentolamine ophthalmic solution, low-dose estrogen weekly patch, and fast-acting meloxicam in the U.S., and sotagliflozin in Australia and Canada. Key Phase III programs like cenerimod and selatogrel are nearing full enrollment, with readouts expected in late 2026 or early 2027. The generic pipeline and established brand portfolio are expected to account for over 100 new product approvals globally in 2026.

    03

    Japan Market Focus and Strategy

    Japan is a critical market, historically facing downward pressure from mandatory annual price decreases and structural challenges. Viatris is strategically adding assets like Effexor GAD, pitolisant, and Spydia to transition the region from revenue and EBITDA decline to growth by 2028 and beyond. The mid-year Amitiza LOE in Japan is noted as a headwind for 2026, but the company is confident in the long-term trajectory with new product launches.

    04

    Fast-Acting Meloxicam Launch Strategy

    With an NDA submission imminent following a positive pre-NDA meeting with the FDA, fast-acting meloxicam is poised to address the acute pain market, particularly post-operative and operative pain. The company plans a specialty sales force targeting surgeons, orthopedic surgeons, and dental surgeons, with potential partnerships to expand reach beyond these initial targets. The product is expected to be a long-term contributor, potentially into the 2030s, due to exclusivity and intellectual property protection, with opioid-sparing language anticipated in the label.

    05

    Capital Allocation and Financial Flexibility

    Viatris expects robust cash flow in 2026, providing over $2.5 billion for deployment, including excess cash on hand and net proceeds from the Biocon monetization. Priorities include accretive in-market business development, continued shareholder returns (dividends), and debt paydown to achieve a gross leverage range of 2.8x to 3.2x. The company is not focused on acquiring early-stage pipeline assets but rather commercial-stage assets that can drive near-term growth.

    06

    2026 Outlook and Phasing

    The company expects 2026 to be a stabilization year, with total revenues and adjusted EBITDA growing approximately 2%. New product revenues are projected at $450 million to $550 million. The second half of 2026 is expected to be stronger for revenues, adjusted EBITDA, and adjusted EPS due to product seasonality and launch timing, while Q1 will be the lowest for revenues, gross margins, and free cash flow, impacted by working capital, one-time📎 operating cash costs, and transaction/restructuring costs.

    AI-generated summary of the company’s earnings call. Not investment advice.