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    Earnings call· Oct 2025(Q4 FY25)

    AGILENT TECHNOLOGIES, INC. A

    Nov 24, 2025 Source

    Executive summary

    Agilent Q4 FY25 — Strong Core Growth Driven by LC/MS and CDMO Performance

    Agilent delivered strong Q4 FY25 results, exceeding revenue guidance with broad-based momentum driven by LC/MS demand, CDMO performance, and a robust instrument replacement cycle. The company's Ignite operating system contributed to significant margin expansion and operational efficiencies. While facing headwinds in China and Academia & Government, Agilent is poised for continued growth in FY26, leveraging innovation, commercial execution, and improving end markets, despite a higher tax rate.

    Highlights

    5
    • Q4 revenue of $1.86 billion, growing 7.2% on a core basis, exceeded the high end of guidance.

    • LC/MS growth was over 50% in Q4, driven by the successful ramp of the Pro iQ LC/MS platform.

    • The Pharma market demonstrated strong performance, growing 12% in Q4.

    • The specialty CDMO business grew over 40% on a core basis during Q4, contributing nearly 20% of LDG revenue.

    • The Ignite operating system delivered over 200 basis points of sequential operating margin improvement, contributing to over $150 million in annualized savings.

    Concerns

    3
    • China revenue declined 4% in Q4, falling below the company's low single-digit growth expectations.

    • The Academia and Government end market declined 10% in Q4, primarily due to U.S. federal spending reductions impacting instrument sales.

    • FY26 EPS guidance includes a 3 percentage point headwind from a one-time step-up in the tax rate, reflecting new global minimum tax regulations.

    Guidance & targets

    22
    CategoryTargetConfidence
    Full-year FY26 Core Revenue Growth
    4% to 6%
    high materiality
    High
    Full-year FY26 Reported Revenue
    $7.3 billion to $7.4 billion
    high materiality
    High
    Full-year FY26 Operating Margin Expansion
    75 basis points
    high materiality
    High
    Full-year FY26 Non-GAAP EPS
    $5.86 and $6.00
    high materiality
    High
    Full-year FY26 Tax Rate
    14.5%
    medium materiality
    High
    Full-year FY26 Other Income
    $30 million
    low materiality
    High
    Full-year FY26 Diluted Shares Outstanding
    284 million
    low materiality
    High
    Full-year FY26 Operating Cash Flow
    $1.6 billion to $1.7 billion
    medium materiality
    High
    Full-year FY26 Capital Expenditures
    $500 million
    medium materiality
    High
    Q1 FY26 Reported Revenue
    $1.79 billion to $1.82 billion
    high materiality
    High
    Q1 FY26 EPS
    $1.35 to $1.38
    high materiality
    High
    Full-year FY26 Pharma End Market Growth
    High single-digit growth
    medium materiality
    High
    Full-year FY26 Applied Markets End Market Growth
    Mid-single-digit growth
    medium materiality
    High
    Full-year FY26 Diagnostics and Clinical End Market Growth
    Mid-single-digit growth
    medium materiality
    High
    Full-year FY26 Academia and Government End Market Growth
    Low single-digit decline
    medium materiality
    High
    Full-year FY26 Life Science and Diagnostics Markets Group (LDG) Growth
    Mid-single-digit
    medium materiality
    High
    Full-year FY26 Agilent CrossLabs Group (ACG) Growth
    Mid-single-digit
    medium materiality
    High
    Full-year FY26 Applied Markets Group (AMG) Growth
    Low single-digit
    medium materiality
    High
    Full-year FY26 Americas Geography Growth
    Mid- to high single-digit growth
    medium materiality
    High
    Full-year FY26 Europe and Asia ex China Geography Growth
    Mid-single-digit growth
    medium materiality
    High
    Full-year FY26 China Geography Growth
    Flat
    medium materiality
    High
    Specialty CDMO Growth
    Mid-teens growth
    medium materiality
    High

    Segment performance

    16
    SegmentRevenueYoYQoQMargin
    Life Science and Diagnostics Markets Group (LDG)
    Growth was well ahead of guidance, bolstered by strong performance in LC and LC/MS instruments and robust CDMO results.
    LC and LC/MS instruments: strong performanceCDMO results: robust
    11%
    Applied Markets Group (AMG)
    Growth was as expected, led by high single-digit growth in GC and GCMS, benefiting from the instrument replacement cycle.
    GC and GCMS growth: high single-digit
    3%
    Agilent CrossLab Group (ACG)
    Growth was in line with guidance, with strong performance in the rest of the world offset by declines in China.
    Rest of the world growth: high single-digitChina growth: mid-single-digit decline
    6%
    Americas
    Saw healthy growth with broad end-market strength outside Academia and Government.
    11%
    Europe
    Saw healthy growth with broad end-market strength outside Academia and Government.
    11%
    China
    Results were below low single-digit growth expectations, though revenue contributions remained stable. All markets were down low to mid-singles except A&G (up 5%).
    $300 million per quarter (stable)-4%
    Rest of Asia, ex China
    4%
    India
    Exhibited balanced strength across end markets.
    Pharma growth: double-digitApplied markets growth: >20%
    High teens
    Pharma
    The Agilent team leveraged improving conditions and customer-centric solutions. Performance was driven by oligo therapeutic developments, peptide like GLP-1, and Infinity III.
    LC growth: low double-digitLC/MS platforms growth: mid-teens
    12%
    Biotech
    Saw a nice pickup in spending, led by large accounts, with U.S. biotech recovery starting in well-funded large caps.
    Growth ex CDMO: low double digits
    Low 20s
    Specialty CDMO
    Continues to be a differentiated growth driver. Capacity increases at BIOVECTRA enabled a record Q4.
    LDG revenue contribution: nearly 20%Commercial programs contribution to NASD revenue: 60%
    >40%
    Chemical and Advanced Materials
    Continued strong demand in Americas and Europe, with customers investing in capital equipment for semiconductor market reshoring.
    7%
    Diagnostics and Clinical
    A durable mid- to high single-digit performer, with upside potential as the new Dako Omnis family penetrates medium and low throughput labs.
    7%
    Environmental and Forensics
    Driven by the approaching implementation of a revised EU drinking water directive and commercial labs spending capital budgets. PFAS growth increasingly coming from food and CAM.
    PFAS business growth: high single digits (Q4), almost 40% (FY25)
    9%
    Food
    Finished a strong year.
    7%
    Academia and Government
    U.S. federal spending reductions had an increased impact on instrument spending in the U.S. Americas down mid-teens, rest of world down mid-single digits.
    Annual revenue contribution: 7% to 8%
    -10%

    Operational metrics

    32
    Core Revenue Growth
    7.2%6th consecutive quarter of acceleration
    Q4 FY25
    Reported Revenue Growth
    9.4%
    Q4 FY25
    Currency Impact on Revenue
    0.9%favorable
    Q4 FY25
    M&A Impact on Revenue
    1.3%
    Q4 FY25

    The BIOVECTRA acquisition is reflected in core growth starting in October.

    Gross Margin
    54.1%up 100 bps sequentially, down 100 bps YoY
    Q4 FY25

    Year-over-year decline due to tariff headwinds.

    Operating Margin
    27.2%up >200 bps sequentially
    Q4 FY25

    Driven by leverage on volume, strong pricing, and tariff mitigation, despite absorbing an incremental 60 bps sequential headwind from performance-driven variable pay.

    Operating Margin Expansion (adjusted for variable pay)
    270 bpssequential expansion
    Q4 FY25

    Would have been achieved absent the variable pay dynamics, well above guide of 230 bps.

    EPS
    $1.59up 9% YoY
    Q4 FY25

    Above the midpoint of guidance.

    Capital Expenditures
    $93 million
    Q4 FY25
    Share Repurchases
    $85 million
    Q4 FY25
    Dividends Paid
    $70 million
    Q4 FY25
    Dividend Increase
    3%
    Recent

    Increased industry-leading dividend.

    Net Leverage Ratio
    0.8
    Q4 FY25

    Points to a robust balance sheet with ample room for capital deployment.

    Ignite Annualized Savings
    >$150 million
    Annualized

    Delivered through the Ignite operating system.

    LCMS Growth (single quad)
    >50%
    Q4 FY25

    Driven by the Pro iQ LC/MS.

    Sales Leads from Service Team
    30%
    Current

    Percentage of all sales leads generated from insights from the service team.

    Order Conversion Rate (service leads)
    >doublevs. rest of sales funnel
    Current
    AI in Engineering Drawings
    80%
    Current

    AI generates engineering drawings based on product specifications and customer needs.

    Tariff Mitigation
    Fully mitigated
    FY26

    Expected to be achieved over the course of the year using cost savings and pricing actions.

    GLP-1 Revenue
    $40 million
    Q4 FY25
    GLP-1 Revenue (Full Year)
    $130 million
    FY25
    GLP-1 Analytical Lab Growth
    20%
    Q4 FY25
    GLP-1 Analytical Lab Growth (Full Year)
    40%
    FY25
    Instrument Book-to-Bill
    >17th consecutive quarter
    Q4 FY25
    Pharma Reshoring Addressable Market Opportunity
    $1 billion
    By 2030

    Orders expected to materialize by the end of FY26.

    Pricing Improvement
    150 bps
    Q4 FY25
    China Stimulus (SAM tender) Orders
    $10 million
    Q1 FY26

    Expected in Q1 FY26, but excluded from FY26 guide for prudence. Win rate of 50% on port round tenders.

    U.S. A&G Instrument Sales Growth
    Down mid-20s
    Q4 FY25

    Due to U.S. federal spending reductions.

    U.S. A&G Chemistries & Services Growth
    Low single-digit growth
    Q4 FY25

    Indicates reasonable lab usage.

    Large Molecule Growth
    ~10%
    Q4 FY25

    Roughly 50% split with small molecule.

    Small Molecule Growth
    ~10%
    Q4 FY25

    Roughly 50% split with large molecule.

    Lunar New Year Impact on China Q1 FY26 Revenue
    -700 bpsyear-over-year impact
    Q1 FY26

    Due to reduced [indiscernible] volume, offset by favorable Lunar New Year timing.

    Industry KPIs

    10
    MetricValueDetails
    Revenue EPS guidanceFY26 Revenue: $7.3B-$7.4B (reported), 4%-6% (core growth); FY26 EPS: $5.86-$6.00 (5%-7% growth)USD, %
    China revenue exposure-4%%
    Pricing price realization150 bpsbps
    Diagnostics testing demand7%%
    M a contribution synergies1.3%%
    Segment organic revenue growthLDG: 11%; AMG: 3%; ACG: 6%%
    Bioprocessing orders book to bill>1
    Reshoring US manufacturing tailwind$1 billionUSD
    Instruments vs consumables services mixLC: double-digit growth (H2 FY25); LC/MS: mid-teens growth (Q4 FY25); GC/GCMS: high single-digit growth (Q4 FY25); A&G Chemistries & Services (Americas): low single-digit growth (Q4 FY25)%
    Organic core revenue growth by end marketPharma: 12%; Biotech: Low 20s (low double digits ex CDMO); Chemical and Advanced Materials: 7%; Diagnostics and Clinical: 7%; Environmental and Forensics: 9%; Food: 7%; Academia and Government: -10%%

    Product announcements

    3
    ProductTypeDetails
    Infinity IIIlaunch
    Pro iQ LC/MSlaunch
    Altura bio-inert LC columnlaunch

    Deals & partnerships

    1
    BIOVECTRAIntegration of the acquired CDMO business.

    The integration of BIOVECTRA has been highly productive, which bodes well for future M&A. It is a key driver for the specialty CDMO business, particularly in GLP-1 related revenue.

    Risks & headwinds

    6
    China Revenue DeclineQ4 FY25, FY26

    4% decline in Q4 FY25

    Mitigation: Expect FY26 to be flat; taking a prudent approach by substantially moving stimulus benefits out of FY26 revenue guidance.

    Academia and Government End Market DeclineQ4 FY25, FY26

    10% decline in Q4 FY25 (Americas down mid-teens, rest of world down mid-single digits)

    Mitigation: Expect continued softness in FY26 in Americas as U.S. federal spending reductions continue; it is the smallest market, about 1% of overall U.S. business.

    Tariff HeadwindsFY26

    100 bps gross margin impact YoY in Q4 FY25

    Mitigation: Highly confident to fully mitigate current tariffs in FY26 through cost savings and pricing actions, enabled by the Ignite operating system.

    Tax Rate IncreaseFY26

    2.5% increase (to 14.5%) in FY26, resulting in a 3 percentage point EPS growth headwind

    Mitigation: Offsetting the incremental tax burden through operating performance above the line and leveraging Ignite and global network strategy.

    Tougher ComparablesFY26

    Stronger baseline comparison for FY26

    Mitigation: FY26 guidance of 4% to 6% core growth is considered prudent given this factor.

    Macro UncertaintyFY26

    Unquantified

    Mitigation: FY26 guidance is set prudently to account for ongoing macro uncertainty.

    What to watch in Q1 FY26

    5

    Small and Mid-sized Biotech Funding/M&A

    FY26
    CurrentImproving funding backdrop, recent M&A exits, but too early to call an inflection.
    TargetContinued improvement and broadening of recovery.

    Why it matters

    Indicates broader recovery in a key end market, impacting instrument and service demand.

    And while it's too soon to call an inflection, the accelerating pace of M&A and improving funding environment into October bodes well for small and midsized biotech customers in FY '26.

    Q&A highlights

    7

    How did BIOVECTRA perform against guidance, and is the increased CapEx for CDMO expansion?

    BIOVECTRA performed strongly in Q4, driven by GLP-1 business, meeting full-year expectations. The incremental $100 million CapEx is specifically for increasing NASD capacity and consumable expansion.

    So the incremental $100 million investment is really around incremental NASD capacity as well as incremental consumable expansion.

    asked by Tycho Peterson · answered by Adam Elinoff

    3 min read7 chapters

    Detailed Narrative

    01

    Ignite Operating System Drives Efficiency and Growth

    Agilent's Ignite operating system, launched at the start of FY25, has significantly improved execution and fostered a new mindset. It enhanced top-line growth through an enterprise pricing program, more than doubling price growth compared to FY24. Ignite also led to faster decision-making, meaningful procurement cost savings through global vendor contracts, and enabled a rapid, coordinated response to global tariff changes, resulting in over $150 million in annualized savings. This system has also strengthened organizational readiness for M&A integration, exemplified by the successful BIOVECTRA integration.

    02

    Innovation and Product Success Fueling Performance

    Customer-focused innovation was a key driver of success, with products like the next-generation Infinity III delivering up to 30% productivity improvement and driving double-digit LC growth in H2 FY25. The Pro iQ LC/MS saw an 'amazing ramp,' contributing to over 50% LCMS growth in Q4. The recently introduced Altura bio-inert LC column also experienced rapid adoption, with orders an order of magnitude greater than past column launches, indicating strong demand for increased sensitivity in applications like oligos and GLP-1s.

    03

    Strengthened Customer Intimacy and Commercial Model

    Agilent's unified sales and service model is a cornerstone of its success, fostering deep customer relationships. Insights from the service team now account for 30% of all sales leads, which convert at more than double the rate of other sales funnel channels. The company is further enhancing customer intimacy by deploying AI within its CRM for predictive insights and personalized content, and using virtual agents to complement on-site support in select markets.

    04

    Pharma and Biotech Market Recovery Underway

    The Pharma market grew 12% in Q4, benefiting from reduced uncertainty around MFN tariff deals and strong product offerings. Biotech spending increased in the low 20s (low double digits excluding CDMO), with recovery starting in well-funded large caps. While still early, improving funding and accelerating M&A activity bode well for small and mid-sized biotech customers in FY26, though it's too soon to call a full inflection point.

    05

    GLP-1 and Reshoring as Future Growth Drivers

    GLP-1 related revenue reached $40 million in Q4, split 60% from the BIOVECTRA CDMO business and 40% from analytical tools, contributing to a total of $130 million for FY25. Pharma reshoring represents a significant opportunity, with an estimated $1 billion addressable market for Agilent by 2030, and initial orders expected to materialize by the end of FY26. The company is actively engaged in conversations with pharma companies regarding R&D and tech investments for reshoring initiatives.

    06

    Navigating China and Academia & Government Headwinds

    China revenue declined 4% in Q4, falling short of low single-digit growth expectations, with declines in food and environmental offsetting growth in biopharma and CAM. The company expects China to be flat in FY26, taking a prudent approach by excluding substantial stimulus benefits from guidance. The Academia and Government end market declined 10% in Q4 due to U.S. federal spending reductions, with continued softness expected in FY26, particularly in the Americas.

    07

    Tariff Mitigation and Tax Rate Impact on FY26 Outlook

    Agilent expects to fully mitigate current tariffs in FY26 through a combination of cost savings and pricing actions. However, FY26 EPS guidance includes a 3 percentage point headwind from a 2.5% increase in the tax rate to 14.5%. This increase is attributed to new global minimum tax regulations, including Pillar 2 and OB3, and other jurisdictional changes, which have now solidified in the company's tax provision.

    AI-generated summary of the company’s earnings call. Not investment advice.