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MCMCK

McKesson (MCK) Q3 FY26 earnings call: guidance and Q&A

Earnings call· Dec 2025 (Q3 FY26)· Health Care· Feb 4, 2026

Source: earnings call transcript

Executive summary

McKesson Q3 FY26 — Double-Digit Growth and Raised Full-Year EPS Guidance

McKesson delivered a strong third quarter, driven by robust performance in oncology, biopharma services, and North American distribution. The company raised its full-year EPS guidance, reflecting confidence in its strategic priorities and operational execution, including significant investments in technology and automation to enhance efficiency and customer experience. Portfolio optimization continues with the planned Medical-Surgical separation and the completed European exit.

Highlights

5
  • Consolidated revenues increased 11% to $106.2 billion.

  • Adjusted EPS increased 16% to $9.34.

  • Full-year EPS guidance raised to $38.80-$39.20, representing 17%-19% year-over-year growth.

  • Oncology and Multispecialty segment revenue increased 37% to $13 billion, with operating profit up 57%.

  • Operating expenses as a percentage of gross profit improved by 138 basis points.

Concerns

1
  • Medical-Surgical Solutions operating profit decreased 10% to $265 million, reflecting lower volumes across physician office settings and lower incidence of seasonal illness.

Guidance & targets

CategoryTargetConfidence
Full-year FY26 Adjusted EPS
$38.80 to $39.20
high materiality
High
Full-year FY26 Revenue Growth
12% to 16%
high materiality
High
Full-year FY26 Operating Profit Growth
13% to 17%
high materiality
High
Full-year FY26 North American Pharmaceutical Revenue Growth
10% to 14%
medium materiality
High
Full-year FY26 North American Pharmaceutical Operating Profit Growth
8% to 12%
medium materiality
High
Full-year FY26 Oncology and Multispecialty Revenue Growth
29% to 33%
medium materiality
High
Full-year FY26 Oncology and Multispecialty Operating Profit Growth
51% to 55%
medium materiality
High
Full-year FY26 Prescription Technology Solutions Revenue Growth
9% to 13%
medium materiality
High
Full-year FY26 Prescription Technology Solutions Operating Profit Growth
14% to 18%
medium materiality
High
Full-year FY26 Medical-Surgical Solutions Revenue Growth
Lower end of 2% to 6%
medium materiality
Medium
Full-year FY26 Medical-Surgical Solutions Operating Profit Growth
Lower end of 2% to 6%
medium materiality
Medium
Full-year FY26 Corporate Expenses
$620 million to $650 million
low materiality
High
Full-year FY26 Interest Expense
$215 million to $235 million
low materiality
High
Full-year FY26 Income Attributable to Noncontrolling Interest
$230 million to $250 million
low materiality
High
Full-year FY26 Effective Tax Rate
Approximately 19%
low materiality
High
Full-year FY26 Free Cash Flow
Approximately $4.4 billion to $4.8 billion
high materiality
High
Full-year FY26 Share Repurchases
Approximately $2.5 billion
high materiality
High
Full-year FY26 Weighted-Average Diluted Shares Outstanding
Approximately 124 million
low materiality
High
Medical-Surgical Business IPO Timeline
Second half of calendar 2027
high materiality
Medium
Norway Operations FY26 Revenue Contribution
Approximately $1 billion
low materiality
High
Norway Operations FY26 Adjusted Operating Profit Contribution
Approximately $70 million
low materiality
High
Norway Operations FY26 Adjusted EPS Accretion
Approximately $0.10
low materiality
High
Q4 FY26 Prescription Technology Solutions Incremental Technology Investments Cost
Approximate $0.05
low materiality
High

Segment performance

SegmentRevenueYoYQoQMargin
North American Pharmaceutical
Driven by higher prescription volumes, including higher volumes across retail national account customers and continued specialty product distribution strength. Operating profit increased 6%, benefiting from growth in specialty products distribution, including to health systems. Prior year included a $19 million benefit from held-for-sale accounting related to Canada-based Rexall and Well.ca businesses.
$88.3 billion9%—$872 million
Oncology and Multispecialty
Driven by strong provider growth, expanded specialty distribution, and contributions from acquisitions (PRISM and Core Ventures) completed this fiscal year. Operating profit increased 57%, led by growth in provider solutions and specialty distribution, including contributions from acquisitions.
Acquisitions contribution to revenue growth: 13%Organic operating profit growth (excluding acquisitions): 15%
$13 billion37%—$366 million
Prescription Technology Solutions
Supported by higher prescription volumes across third-party logistics and technology services businesses. Operating profit rose 18%, driven by continued demand for access solutions, including prior authorization services.
$1.5 billion9%—$277 million
Medical-Surgical Solutions
Revenue growth driven by higher specialty pharmaceutical volumes. Operating profit decreased 10%, reflecting lower volumes across physician office settings and lower incidence of seasonal illness.
$3 billion1%—$265 million
Other (Norway operations)
Contributed $0.05 of adjusted earnings per diluted share due to held-for-sale accounting in Q3. Divestiture completed on January 30, marking the final step in the exit from Europe.
Adjusted earnings per diluted share accretion from held-for-sale accounting: $0.05
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MCK operating KPIs by quarter

MCK operating KPIs stated on its earnings calls, by fiscal quarter
KPI Dec 2024 Q3 FY25 Jun 2025 Q1 FY26 Sep 2025 Q2 FY26This call Dec 2025 Q3 FY26 Mar 2026 Q4 FY26 Jun 2026 Q1 FY27Change vs prior quarter
Providers US Oncology Network
2,750+ We're pleased to see the continued expansion growing to over 2,750 providers across 640 sites of care in 31 different states. Source: earnings call transcript
~3,300 This marks an important step forward in our efforts to expand access to exceptional cancer care in local communities, growing the footprint of the US Oncology Network to approximately 3,300 providers across 700 sites in 30 states. Source: earnings call transcript
3,300+ The US Oncology Network has been leading the cancer care transformation for more than 15 years and is now supporting over 3,300 providers across more than 700 sites across the country. Source: earnings call transcript
~3,400 Today, the US oncology network has approximately 3,400 providers, and PRISM Vision brings together over 200 providers in retina and ophthalmology. Source: earnings call transcript
—
~3,400 The US Oncology Network grew to approximately 3,400 providers and treats more than 2 million patients annually. Source: earnings call transcript
—
Sites of care US Oncology Network
640 We're pleased to see the continued expansion growing to over 2,750 providers across 640 sites of care in 31 different states. Source: earnings call transcript
700 This marks an important step forward in our efforts to expand access to exceptional cancer care in local communities, growing the footprint of the US Oncology Network to approximately 3,300 providers across 700 sites in 30 states. Source: earnings call transcript
700+ The US Oncology Network has been leading the cancer care transformation for more than 15 years and is now supporting over 3,300 providers across more than 700 sites across the country. Source: earnings call transcript
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Employees —
45K Everything we achieve is made possible by the dedication and the commitment of our 45,000 employees. Source: earnings call transcript
——
43K As we close out a really great fiscal '26, I want to thank the 43,000 McKesson employees for their commitment to the work they do every day to advance our mission. Source: earnings call transcript
——
Providers PRISM Vision———
200+ Today, the US oncology network has approximately 3,400 providers, and PRISM Vision brings together over 200 providers in retina and ophthalmology. Source: earnings call transcript
—
200+ PRISM Vision brings together over 200 providers in 97 locations, helping expand access to high-quality retina and ophthalmology care, again, in the community setting. Source: earnings call transcript
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Operating figures the company stated on at least two of the calls shown, checked against each call's transcript. Click a figure to read the sentence. A dash means it was not stated that quarter.

Deals & partnerships

Norway operations Divestiture

Completed the divestiture of retail and distribution businesses in Norway on January 30. This marks the final step in McKesson's planned exit of Europe.

Medical-Surgical business Divestiture (IPO)

Progressing in the separation of the Medical-Surgical business. Transition service agreements are now in place across the enterprise. The company is tracking towards an IPO by the second half of calendar 2027, subject to market conditions and customary regulatory approvals.

PRISM Vision and Core Ventures Acquisition

Acquisitions completed in the first quarter of fiscal 2026. These acquisitions are contributing meaningfully to the strong performance of the Oncology and Multispecialty segment and are performing well, maybe slightly ahead of the acquisition case.

Risks & headwinds

Medical-Surgical segment performance variability Q3 FY26

Operating profit decreased 10% to $265 million

Mitigation:Closely tracking the development of the current illness season and executing the separation of the Medical-Surgical segment with discipline and focus.

GLP-1 distribution revenue variability Ongoing

Growth may vary from quarter-to-quarter

Medical-Surgical IPO market conditions and regulatory approvals Second half of calendar 2027

IPO by the second half of calendar 2027, subject to market conditions and customary regulatory approvals

Prescription Technology Solutions revenue and operating profit trend variability Quarter-to-quarter

Not linear, can vary due to utilization trends, timing and trajectory of new product drug launches, program support requirements, product delays, supply chain dynamics, payer utilization and formulary requirements, annual verification programs, and investment timing.

Q&A highlights

Can you elaborate on specific technology investments driving productivity in annual verification season and the long-term margin opportunity for the Prescription Technology Solutions segment?

Management highlighted investments in AI and automation to streamline workflows, such as automating emails and building digitally native tools for new regulatory requirements like DSCSA, which autonomously resolves 75% of inquiries. They noted that half of RxTS revenue comes from technology services supporting biopharma, and positioning the portfolio to automate these services will continue to improve margin trajectory, which has already seen 130 bps growth YoY.

“we look to position the portfolio to continue to automate capabilities and automated services and products on behalf of our biopharma partners. And I think we like the trajectory that we're seeing in the business. If you look at the segment, we've seen operating margins grow over 130 basis points year-over-year.”

asked by Allen Lutz · answered by Britt Vitalone

2 min read 5 chapters

Detailed narrative

Strategic Growth Pillars Momentum

McKesson is seeing continued momentum in its oncology and multispecialty business, supporting a network of approximately 3,400 U.S. oncology providers and over 200 PRISM Vision providers. The integration of Florida Cancer Specialists and PRISM Vision is progressing well, contributing significantly to segment performance.

The company emphasizes its role in advancing community-based cancer care and leveraging its platform for biopharma partnerships, as highlighted by the recent 'advancing Community Oncology report' and the inaugural McKesson Accelerate conference with over 1,500 industry leaders.

Biopharma Services Expansion

The Prescription Technology Solutions segment added over 50 new programs across 43 unique brands, demonstrating strong demand for its access and affordability solutions. Investments are focused on modernizing services, including simplifying electronic patient enrollment for specialty medications, reducing processing time from days or weeks to minutes, and improving accuracy.

This evolving suite of solutions aims to accelerate patient authorization workflows, speed up medication access, and improve affordability through automated financial assistance searches.

North American Pharmaceutical Strength

The North American Pharmaceutical segment shows strong broad-based momentum, supported by stable utilization trends, specialty product strength, and operational excellence. The company is investing in refrigerated capacity expansion across its network, aiming for over 50% increase at many forward distribution centers, and leveraging AI and automation for efficiency.

An AI chat tool for DSCSA inquiries prevented 75% of escalations, materially improving first contact resolution and customer experience.

Portfolio Optimization and Shareholder Value

McKesson is progressing with the separation of its Medical-Surgical business, with transition service agreements now in place, targeting an IPO by the second half of calendar 2027. The company also completed the divestiture of its Norwegian business, marking its full exit from Europe.

These portfolio actions have streamlined the company, sharpened its strategy, and contributed to a significant increase in return on invested capital, now exceeding 30%.

Technology and Efficiency Gains

McKesson is making targeted investments in technology, automation, and AI-driven capabilities across the enterprise to drive efficiencies and enhance customer experience. In the annual verification season, full-time employees are successfully supporting 120 more patients than last year due to these investments.

The company also highlighted the modernization of contacts and digital operations in Canada, including agent assist and enhanced live chat, demonstrating strong results with near 100% service accuracy.

Summary of the company's earnings call; see how call summaries are prepared. Not investment advice.