Jun 2026 (Q2 FY26) — Aug 6, 2026
Praxis Precision Medicines Q2 FY26 — Dual NDA Progress and Commercial Readiness
Read the full callPraxis Precision Medicines earnings: last reported Thu, 6 Aug 2026, for the quarter ended Jun 2026.
Reported
Each figure keeps its basis and period; nothing is filled in.
| Metric | Value | Change | Basis | Period | Note |
|---|---|---|---|---|---|
| Revenue | Quarterly, as filed | Quarter to Jun 2026 | Not in the filed figures for the quarter to jun 2026. No older figure is substituted. | ||
| Operating margin | Operating profit / revenue | Quarter to Jun 2026 | Not in the filed figures for the quarter to jun 2026. No older figure is substituted. | ||
| Net profit | -83.7 | Quarterly, as filed | Quarter to Jun 2026 | Profit after tax as filed. The year-earlier figure was zero or a loss, so no percentage is shown. |
Price
1Y: $52.52 on 14 Oct 2025 → $248.24. High $386.33 (12 Aug 2026), low $52.52 (14 Oct 2025).
Overview
Call summaries
Praxis Precision Medicines Q2 FY26 — Dual NDA Progress and Commercial Readiness
Read the full callPraxis Precision Medicines Q1 FY26 — Late-Stage Assets Progress, Commercial Ramp, and Pipeline Catalysts
Read the full callEvery analysed call
Financials
Net profit, year on year: −18% (quarter to jun 2026 against jun 2025).
| Line item | Sep 2024 | Dec 2024 | Mar 2025 | Jun 2025 | Sep 2025 | Dec 2025 | Mar 2026 | Jun 2026 |
|---|---|---|---|---|---|---|---|---|
| Sales | 0 | 7 | 0 | 0 | 0 | 0 | — | — |
| Operating profit | -57 | -64 | -75 | -76 | -78 | -97 | -106 | -97 |
| Operating margin | −18819.5% | −857.0% | — | — | — | — | — | — |
| Other income | 5 | 5 | 5 | 5 | 4 | 8 | 13 | 13 |
| Net profit | -52 | -59 | -69 | -71 | -74 | -89 | -93 | -84 |
| EPS ($ per share) | -2.75 | — | -3.29 | -3.31 | -3.36 | — | -3.20 | -2.87 |
| Line item | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|
| Equity capital | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Reserves | -81 | -150 | -317 | -531 | -654 | -837 | -1,140 |
| Total liabilities | 8 | 16 | 42 | 39 | 18 | 38 | 60 |
| Fixed assets | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
| Investments | — | — | — | — | — | 177 | 242 |
| Total assets | 48 | 303 | 293 | 115 | 88 | 483 | 938 |
| Line item | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|
| Cash from operations | -33 | -53 | -125 | -185 | -111 | -132 | -249 |
| Cash from investing | -0 | 0 | -141 | 97 | 39 | -248 | -311 |
| Cash from financing | 60 | 304 | 108 | 10 | 92 | 514 | 702 |
| Net cash flow | 27 | 252 | -157 | -78 | 20 | 134 | 142 |
| Capital expenditure | -0 | 0 | -1 | -0 | -0 | 0 | -0 |
| Free cash flow | -34 | -53 | -126 | -185 | -111 | -132 | -249 |
| Segment | Q1 FY2024 | Q2 FY2024 | Q1 FY2025 | Q2 FY2025 | Q3 FY2025 | Q4 FY2025 | YoY growth latest quarter |
|---|---|---|---|---|---|---|---|
| Reportable | — | — | — | — | — | — | — |
Share of consolidated revenue by quarter. Q4 is the fiscal year less its first three quarters.
See how segments are shifting across companies → Segment Shift
81 filings between Oct 16, 2025 and Jul 8, 2026.
Purchases
None
No insider bought shares.
Sales
$44.27M
28 sales by 4 insiders
43% filed under a 10b5-1 plan — scheduled in advance, not decided on the day
Also filed: 3 gifts.
| Insider | Bought | Sold | Last filing |
|---|---|---|---|
| Adage Capital Management, L.P. | — | $33.20M | Oct 16, 2025 |
| Nemiroff Alex | — | $4.85M | Nov 20, 2025 |
| DeSimone Jill | — | $3.61M | Jun 24, 2026 |
| Mastrocola Lauren | — | $2.61M | Nov 20, 2025 |
| Date | Insider | What | Shares | Value |
|---|---|---|---|---|
| Jul 8, 2026 | Souza Marcio Chief Executive Officer | Gift | 2,600 | $0 |
| Jul 8, 2026 | Souza Marcio Chief Executive Officer | Gift | 20,521 | $0 |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 10 | $3.0K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 120 | $36.4K |
| Jun 24, 2026 | DeSimone Jill Director | Option exercise 10b5-1 plan | 8,566 | $379.0K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 1,279 | $402.8K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 837 | $264.2K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 1,240 | $382.2K |
| Jun 24, 2026 | DeSimone Jill Director | Option exercise 10b5-1 plan | 3,034 | $446.9K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 2,854 | $890.2K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 1,750 | $544.1K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 1,004 | $314.1K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 320 | $97.7K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 504 | $158.1K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 999 | $309.1K |
| Jun 24, 2026 | DeSimone Jill Director | Sale 10b5-1 plan | 683 | $209.5K |
| Jun 10, 2026 | Arbuckle Stuart A Director | Award | 1,371 | $0 |
| Jun 10, 2026 | Norden Gregory Director | Award | 1,371 | $0 |
| Jun 10, 2026 | YOUNG WILLIAM D Director | Award | 1,371 | $0 |
| Jun 10, 2026 | Chodakewitz Jeffrey Director | Award | 1,371 | $0 |
| Jun 10, 2026 | DeSimone Jill Director | Award | 1,371 | $0 |
| Jun 10, 2026 | Cudkowicz Merit Ester Director | Award | 1,371 | $0 |
| Jun 10, 2026 | KINDLER JEFFREY B Director | Award | 1,371 | $0 |
| Jun 10, 2026 | MITCHELL DEAN J Director | Award | 1,371 | $0 |
| May 14, 2026 | Souza Marcio Chief Executive Officer | Award | 126 | $21.2K |
| May 14, 2026 | Nemiroff Alex General Counsel and Secretary | Award | 78 | $13.1K |
| May 14, 2026 | Kelly Timothy Edwin Chief Financial Officer | Award | 121 | $20.3K |
| May 14, 2026 | Sniecinski Megan Chief Operating Officer | Award | 89 | $14.9K |
| May 14, 2026 | Mastrocola Lauren Principal Accounting Officer | Award | 127 | $21.3K |
| Feb 6, 2026 | KINDLER JEFFREY B Director | Award | 478 | $0 |
| Feb 6, 2026 | KINDLER JEFFREY B Director | Award | 688 | $0 |
| Feb 6, 2026 | Arbuckle Stuart A Director | Award | 478 | $0 |
| Feb 6, 2026 | Arbuckle Stuart A Director | Award | 688 | $0 |
| Jan 12, 2026 | Nemiroff Alex General Counsel and Secretary | Tax withheld | 768 | $211.8K |
| Jan 12, 2026 | Mastrocola Lauren Principal Accounting Officer | Tax withheld | 344 | $94.9K |
| Jan 12, 2026 | Sniecinski Megan Chief Operating Officer | Tax withheld | 885 | $244.0K |
| Jan 12, 2026 | Kelly Timothy Edwin Chief Financial Officer | Tax withheld | 943 | $260.0K |
| Jan 10, 2026 | Mastrocola Lauren Principal Accounting Officer | Tax withheld | 367 | $105.9K |
| Jan 10, 2026 | Sniecinski Megan Chief Operating Officer | Tax withheld | 1,087 | $313.5K |
| Jan 10, 2026 | Nemiroff Alex General Counsel and Secretary | Tax withheld | 917 | $264.5K |
| Jan 10, 2026 | Souza Marcio Chief Executive Officer | Tax withheld | 4,252 | $1.23M |
| Jan 10, 2026 | Kelly Timothy Edwin Chief Financial Officer | Tax withheld | 1,335 | $385.1K |
| Jan 8, 2026 | Nemiroff Alex General Counsel and Secretary | Award | 6,875 | $0 |
| Jan 8, 2026 | Mastrocola Lauren Principal Accounting Officer | Award | 3,750 | $0 |
| Jan 8, 2026 | Sniecinski Megan Chief Operating Officer | Award | 9,625 | $0 |
| Jan 8, 2026 | Kelly Timothy Edwin Chief Financial Officer | Award | 8,800 | $0 |
| Jan 8, 2026 | Souza Marcio Chief Executive Officer | Award | 27,640 | $0 |
| Jan 7, 2026 | Nemiroff Alex General Counsel and Secretary | Tax withheld | 89 | $26.0K |
| Jan 7, 2026 | Mastrocola Lauren Principal Accounting Officer | Tax withheld | 35 | $10.2K |
| Jan 7, 2026 | Souza Marcio Chief Executive Officer | Tax withheld | 405 | $118.5K |
Source: SEC Form 4 filings. Form 4 reports transactions, not the cap table — absence of filings says nothing about how much an insider owns, and a quiet window is not a signal.
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