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VRVRTX

Vertex Pharmaceuticals (VRTX) Q2 FY25 earnings call

Earnings call· Jun 2025 (Q2 FY25)· Health Care· Aug 4, 2025

Source: earnings call transcript

Vertex Pharmaceuticals delivered strong Q2 FY25 results, driven by 12% revenue growth and successful launches of ALYFTREK and JOURNAVX, alongside building global momentum for CASGEVY. The company is rapidly advancing its late-stage pipeline, with multiple pivotal studies underway and regulatory submissions anticipated in 2026 and 2027. While facing regulatory hurdles for a broad PNP label and a clinical setback for VX-993 monotherapy in acute pain, Vertex remains focused on expanding patient reach and diversifying its therapeutic portfolio.

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VRTX operating KPIs by quarter

VRTX operating KPIs stated on its earnings calls, by fiscal quarter
KPIThis call Jun 2025 Q2 FY25 Sep 2025 Q3 FY25 Dec 2025 Q4 FY25Change vs prior quarter
Patients CASGEVY
16 And finally, a total of 29 patients have completed their treatment journey and received their infusions of CASGEVY edited cells, including 16 patients in the second quarter of 2025. Source: earnings call transcript
10 And a total of 39 patients have received their infusions of CASGEVY edited cells, including 10 patients in the third quarter of 2025. Source: earnings call transcript
30 You can see the evidence of this acceleration in our excellent quarter 4 '25 results, where CASGEVY had 111 new patient initiations, 37 patients with first cell collections and 30 patients receiving infusions, driving $54 million in quarterly revenue. Source: earnings call transcript
+200%

Operating figures the company stated on at least two of the calls shown, checked against each call's transcript. Click a figure to read the sentence. A dash means it was not stated that quarter.

Inve summary of the company's earnings call; see how call summaries are prepared. Not investment advice.