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VRVRTX

Vertex Pharmaceuticals (VRTX) Q4 FY25 earnings call

Earnings call· Dec 2025 (Q4 FY25)· Health Care· Feb 12, 2026

Source: earnings call transcript

Vertex Pharmaceuticals delivered robust financial results in Q4 and full year FY25, driven by consistent CF performance and successful diversification into new therapeutic areas like hematological disorders and acute pain. The company is rapidly advancing its pipeline, particularly in renal diseases, with multiple key milestones anticipated in 2026, positioning it for sustained long-term growth and broader patient impact.

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VRTX operating KPIs by quarter

VRTX operating KPIs stated on its earnings calls, by fiscal quarter
KPI Jun 2025 Q2 FY25 Sep 2025 Q3 FY25This call Dec 2025 Q4 FY25Change vs prior quarter
Patients CASGEVY
16 And finally, a total of 29 patients have completed their treatment journey and received their infusions of CASGEVY edited cells, including 16 patients in the second quarter of 2025. Source: earnings call transcript
10 And a total of 39 patients have received their infusions of CASGEVY edited cells, including 10 patients in the third quarter of 2025. Source: earnings call transcript
30 You can see the evidence of this acceleration in our excellent quarter 4 '25 results, where CASGEVY had 111 new patient initiations, 37 patients with first cell collections and 30 patients receiving infusions, driving $54 million in quarterly revenue. Source: earnings call transcript
+200%

Operating figures the company stated on at least two of the calls shown, checked against each call's transcript. Click a figure to read the sentence. A dash means it was not stated that quarter.

Inve summary of the company's earnings call; see how call summaries are prepared. Not investment advice.