Jun 2026 (Q2 FY26) — Jul 30, 2026
Madrigal Pharmaceuticals Q2 FY26 — Rezdiffra Exceeds Expectations with Strong Patient Adds and Robust Sales Growth
Read the full callMadrigal Pharmaceuticals earnings: last reported Thu, 30 Jul 2026, for the quarter ended Jun 2026.
Reported
Each figure keeps its basis and period; nothing is filled in.
| Metric | Value | Change | Basis | Period | Note |
|---|---|---|---|---|---|
| Revenue | 364 | +71.2% YoY | Quarterly, as filed | Quarter to Jun 2026 | Revenue from operations as filed. |
| Operating margin | -15.5 | +6.7 pts YoY | Operating profit / revenue | Quarter to Jun 2026 | For the quarter; a change is in percentage points. |
| Net profit | -57.9 | Quarterly, as filed | Quarter to Jun 2026 | Profit after tax as filed. The year-earlier figure was zero or a loss, so no percentage is shown. |
Price
1Y: $438.9 on 17 Oct 2025 → $447.09. High $602.83 (22 Dec 2025), low $412.35 (3 Nov 2025).
Overview
Call summaries
Madrigal Pharmaceuticals Q2 FY26 — Rezdiffra Exceeds Expectations with Strong Patient Adds and Robust Sales Growth
Read the full callMadrigal Pharmaceuticals Q1 FY26 — Rezdiffra Blockbuster Status & Pipeline Expansion
Read the full callEvery analysed call
Financials
Net profit, year on year: −37% (quarter to jun 2026 against jun 2025).
| Line item | Sep 2024 | Dec 2024 | Mar 2025 | Jun 2025 | Sep 2025 | Dec 2025 | Mar 2026 | Jun 2026 |
|---|---|---|---|---|---|---|---|---|
| Sales | 62 | 103 | 137 | 213 | 287 | 321 | 311 | 364 |
| Operating profit | -116 | -67 | -79 | -47 | -114 | -60 | -93 | -56 |
| Operating margin | −187.1% | −64.8% | −57.8% | −22.2% | −39.7% | −18.6% | −29.8% | −15.5% |
| Interest | 4 | 3 | 3 | 3 | 7 | 8 | 8 | 8 |
| Net profit | -107 | -59 | -73 | -42 | -114 | -59 | -94 | -58 |
| EPS ($ per share) | -4.92 | — | -2.61 | -1.50 | -4.01 | — | -3.25 | -1.99 |
| Line item | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|
| Equity capital | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Reserves | -139 | -223 | -425 | -667 | -963 | -1,336 | -1,802 | -2,090 |
| Total liabilities | 8 | 25 | 47 | 77 | 165 | 235 | 288 | 657 |
| Fixed assets | 0 | 1 | 1 | 1 | 1 | 2 | 2 | 1 |
| Total assets | 485 | 442 | 287 | 273 | 363 | 641 | 1,042 | 1,260 |
| Line item | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|
| Cash from operations | -26 | -42 | -158 | -184 | -225 | -324 | -456 | -190 |
| Cash from investing | -380 | 31 | 160 | -5 | 207 | -503 | -274 | 32 |
| Cash from financing | 314 | 0 | 5 | 171 | 313 | 595 | 735 | 256 |
| Net cash flow | — | — | — | -18 | 295 | -232 | 5 | 99 |
| Capital expenditure | -0 | -0 | -0 | -0 | -0 | -1 | -1 | -0 |
| Free cash flow | -26 | -42 | -158 | -184 | -225 | -326 | -457 | -190 |
| Segment | Q2 FY2025 | Q3 FY2025 | Q1 FY2026 | Q2 FY2026 | YoY growth latest quarter |
|---|---|---|---|---|---|
| Reportable | 100% | 100% | 100% | 100% | +71.2% |
Share of consolidated revenue by quarter. Q4 is the fiscal year less its first three quarters.
See how segments are shifting across companies → Segment Shift
| KPI | Mar 2026 Q1 FY26 | Jun 2026 Q2 FY26 | Change vs prior quarter |
|---|---|---|---|
| Patients Rezdiffra | 42.25K+We ended the first quarter with more than 42,250 active patients on Rezdiffra.Source: earnings call transcript | 49K+That's why we've steadily added patients ending the second quarter with more than 49,000 active patients on Rezdiffra, more than double a year ago.Source: earnings call transcript | — |
Operating figures the company stated on at least two of the calls shown, checked against each call's transcript. Click a figure to read the sentence. A dash means it was not stated that quarter.
233 filings between Nov 5, 2025 and Sep 11, 2026.
Purchases
None
No insider bought shares.
Sales
$81.48M
202 sales by 9 insiders
84% filed under a 10b5-1 plan — scheduled in advance, not decided on the day
Also filed: 1 gift.
| Insider | Bought | Sold | Last filing |
|---|---|---|---|
| FRIEDMAN PAUL A | — | $26.66M | Jan 9, 2026 |
| Taub Rebecca | — | $21.68M | Mar 6, 2026 |
| Sibold William John | — | $10.48M | Sep 11, 2026 |
| BATE KENNETH | — | $8.03M | Nov 5, 2025 |
| Levy Richard S | — | $7.36M | May 22, 2026 |
| Dier Mardi | — | $3.77M | Mar 6, 2026 |
| Huntsman Carole | — | $1.71M | Mar 6, 2026 |
| Soergel David | — | $952.0K | Jun 1, 2026 |
| Date | Insider | What | Shares | Value |
|---|---|---|---|---|
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 368 | $199.3K |
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 687 | $371.4K |
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 761 | $414.6K |
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 160 | $86.0K |
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 60 | $32.0K |
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 218 | $116.8K |
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 106 | $56.6K |
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 120 | $65.6K |
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 1,539 | $837.3K |
| Sep 11, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 1,202 | $652.2K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 160 | $86.8K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 131 | $69.2K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 644 | $344.7K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 396 | $211.5K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 522 | $276.8K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 362 | $196.1K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 512 | $272.9K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 215 | $115.9K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 520 | $279.9K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 505 | $272.8K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 640 | $343.8K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 347 | $183.7K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 1,040 | $557.6K |
| Sep 9, 2026 | Sibold William John President and CEO | Sale 10b5-1 plan | 368 | $195.8K |
| Aug 17, 2026 | Kelley Shannon T General Counsel | Sale | 664 | $341.9K |
| Aug 15, 2026 | REED JOHN C Director | Award | 647 | $0 |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 545 | $296.9K |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 110 | $59.8K |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 140 | $76.0K |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 275 | $150.1K |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 1 | $551 |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 680 | $372.4K |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 280 | $155.4K |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 269 | $147.2K |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 153 | $84.2K |
| Jul 20, 2026 | Sibold William John President and CEO | Sale | 47 | $25.8K |
| Jul 17, 2026 | Sibold William John President and CEO | Option exercise | 50,000 | — |
| Jun 17, 2026 | Brennan Daniel J. Director | Award | 404 | $0 |
| Jun 17, 2026 | BAKER BROS. ADVISORS LP Director | Award | 908 | $0 |
| Jun 17, 2026 | Taub Rebecca Director | Award | 454 | $0 |
| Jun 17, 2026 | BAKER BROS. ADVISORS LP Director | Award | 908 | $0 |
| Jun 17, 2026 | Levy Richard S Director | Award | 454 | $0 |
| Jun 17, 2026 | FOUSE JACQUALYN A Director | Award | 454 | $0 |
| Jun 17, 2026 | Daly James M Director | Award | 454 | $0 |
| Jun 1, 2026 | Soergel David Chief Medical Officer | Sale 10b5-1 plan | 1,042 | $516.6K |
| May 22, 2026 | Levy Richard S Director | Sale 10b5-1 plan | 439 | $225.0K |
| May 22, 2026 | Levy Richard S Director | Sale 10b5-1 plan | 610 | $312.0K |
| May 22, 2026 | Levy Richard S Director | Sale 10b5-1 plan | 151 | $77.1K |
| May 22, 2026 | Levy Richard S Director | Sale 10b5-1 plan | 320 | $162.6K |
| May 22, 2026 | Levy Richard S Director | Sale 10b5-1 plan | 40 | $20.3K |
Source: SEC Form 4 filings. Form 4 reports transactions, not the cap table — absence of filings says nothing about how much an insider owns, and a quiet window is not a signal.
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